TY -的A2 -楚,昆西AU -玫瑰,巴里AU - Tamvakopoulos, George S. AU - Yeung, Eric AU - Pollock, Robin AU - Skinner, John AU - Briggs, Timothy AU - Cannon, Steven PY - 2009 DA - 2010/02/07 TI - Granular Cell Tumours: A Rare Entity in the Musculoskeletal System SP - 765927 VL - 2009 AB - Granular Cell Tumours are rare mesenchymal soft tissue tumoursthat arise throughout the body and are believed to be of neuralorigin. They often present as asymptomatic, slow-growing, benign,solitary lesions but may be multifocal. 1-2% of cases are malignantand can metastasise. Described series in the literature aresparse. We identified eleven cases in ten patients treatedsurgically and followed-up for a period of over 6 years in ourregional bone and soft tissue tumour centre. Five tumours werelocated in the lower limb, four in the upper limb, and two in thetrunk. Mean patient age was 31.2 years (range 8–55 years). Excision was complete in one case, marginal in five cases andintralesional in five cases. No patients required postoperativeadjuvant treatment. Mean follow-up was 19.3 months (range 1–37months). One case was multifocal, but there were no cases of localrecurrence or malignancy. Histopathological andimmunohistochemical analysis revealed the classical granular celltumour features in all cases. We believe this case series to bethe largest of its type in patients presenting to an orthopaedicsoft tissue tumour unit. We present our findings and correlatethem with findings of other series in the literature. SN - 1357-714X UR - https://doi.org/10.1155/2009/765927 DO - 10.1155/2009/765927 JF - Sarcoma PB - Hindawi Publishing Corporation KW - ER -