TY - A2的刘冯盟——他,Linlu AU - Chen Guangxiang盟——郑Ruwen AU -胡,燕盟——陈,秀盟——阮,江海PY - 2020 DA - 2020/12/09 TI -异构针灸效应的译著(KI3)在健康的青年和老人功能连通性:SP - 8884318 VL - 2020 AB -以往研究曾提出针刺不同组间的异质性神经反应，但研究较少。本研究通过功能磁共振成像(functional magnetic resonance imaging, fMRI)，探讨针刺太溪穴(KI3)对健康青年和老年人脑区自发活动和功能连接(functional connectivity, FC)的差异。20名健康青年志愿者和20名健康老年人针刺前静息状态fMRI 10分钟，然后针刺太溪(KI3) 3分钟;在抽出针头后，志愿者们进行了10分钟的第二次功能磁共振成像扫描。采用区域同质性(ReHo)和Power 264图谱进行大规模FC分析，分析脑自发活动的变化。与静息状态相比，两组针刺KI3后ReHo的降低均集中在左侧中央后小叶、右侧中央旁小叶和右侧SMA。此外，HY组的受试者在涉及右侧语言和中央前脑区的ReHo水平下降。而HE组在针刺KI3后，右侧中央后、中央前、左侧边缘上回、SMA及两侧扣带中部ReHo均降低。与静息状态相比，针刺后状态下HY组感觉/躯体运动和皮层下网络平均网络FC较低。 And the internetwork FC between sensory/somatomotor and dorsal attention had significantly decreased after acupuncture. Furthermore, the internetwork FC between subcortical and dorsal attention and between subcortical and cerebellar showed the most obvious elevations after needling in the HY group. In the elder group, both FCs of internetwork and intranetwork primarily involving sensory/somatomotor, cingulo-opercular, and dorsal attention were declined after acupuncture. These results indicated that acupuncture at KI3 had heterogeneous acupuncture effects in different age groups. Our study led to converging evidence supporting the acupuncture effect segregation of different condition subjects and supporting evidence for prevention and treatment with acupuncture in the future. SN - 2090-5904 UR - https://doi.org/10.1155/2020/8884318 DO - 10.1155/2020/8884318 JF - Neural Plasticity PB - Hindawi KW - ER -