TY - JOUR A2 - Ather, Mohammad H. AU - Karan, Dev AU - Dubey, Seema PY - 2016 DA - 2016/06/27 TI - From Inflammation to Prostate Cancer: The Role of Inflammasomes SP - 3140372 VL - 2016 AB - Inflammation-associated studies entice specific attention due to inflammation’s role in multiple stages of prostate cancer development. However, mechanistic regulation of inflammation inciting prostate cancer remains largely uncharacterized. A focused class of inflammatory regulators known as inflammasomes has recently gained attention in cancer development. Inflammasomes are a multiprotein complex that drives a cascade of proinflammatory cytokines regulating various cellular activities. Inflammasomes activation is linked with infection, stress, or danger signals, which are common events within the prostate gland. In this study, we review the potential of inflammasomes in understanding the role of inflammation in prostate cancer. SN - 1687-6369 UR - https://doi.org/10.1155/2016/3140372 DO - 10.1155/2016/3140372 JF - Advances in Urology PB - Hindawi Publishing Corporation KW - ER -